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Abstract #2579

A Novel Radiofrequency Pulse Design for Improving Flip-Angle Uniformity in Ultra-High Field MRI

Jason E. Moore1, Marcin Jankiewicz1,2, Huairen Zeng1,2, Adam W. Anderson1,3, Malcolm J. Avison1,3, E Brian Welch1,4, John C. Gore1,3

1Institute of Imaging Science, Vanderbilt University, Nashville, TN, USA; 2Department of Radiology, Vanderbilt University; 3Department of Biomedical Engineering, Vanderbilt University; 4Philips Healthcare, Cleveland, OH, USA

A pulse design method involving a composite of numerous block pulses with amplitude and phases subject to numerical optimization is introduced with the goal of achieving a uniform flip angle distribution across a wide range of field strengths. Possible applications include B1+ insensitive excitation and refocusing at ultra-high field.