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Abstract #2661

Variable Flip Angle Schedules for Detecting Prepared Longitudinal Magnetization in Snapshot Balanced SSFP

Travis B. Smith1, Zungho Zun1, Eric Wong2, Krishna S. Nayak1

1Department of Electrical Engineering, University of Southern California, Los Angeles, CA, USA; 2Departments of Radiology and Psychiatry, University of California, San Diego, La Jolla, CA, USA

Tissue characterization by MRI often involves the subtraction of images obtained with and without a preparation of the longitudinal magnetization (e.g. T2 preparation, arterial spin labeling, and diffusion preparation). Studies that use snapshot balanced steady state free precession typically utilize a brief catalyzation and constant flip angle during acquisition to reach the steady state more quickly. We introduce variable flip angle schedules optimized for the detection of differences in the longitudinal magnetization of the tissue of interest based on its relaxation times. In myocardium, this approach is shown to achieve 18% higher SNR in difference images compared to the conventional approach.