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Abstract #2682

IDEAL at 7T in Mice Using Asymmetric Spin Echo and Gradient Echo Acquisitions

David H. Johnson1, Sreenath P. Narayan1, David L. Wilson1,2, Chris A. Flask1,2

1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA; 2Radiology, University Hospitals of Cleveland, Cleveland, OH, USA

An IDEAL acquisition based on an asymmetric spin echo acquisition (aSE) was developed for imaging mice on a 7T small animal MRI scanner. A short delay (79us - 790us) was inserted between the refocusing pulse and the readout gradient in a standard spin echo acquisition to introduce fat-water phase shift appropriate for IDEAL estimation of separate fat and water images. The aSE-IDEAL technique generated images with dramatically reduced susceptibility artifacts and improved overall image SNR in comparison to conventional spoiled gradient echo (i.e., FLASH) IDEAL images.