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Abstract #2686

TurboCRAZED BOLD Imaging Detects Specific Activation in the Rat Brain After Somatosensory Stimulation at 16.4 Tesla

David Z. Balla1, Hannes M. Wiesner1, Gunamony Shajan1, Cornelius Faber2, Rolf Pohmann1

1High-Field MR Center, Max-Planck-Institute for Biological Cybernetics, Tuebingen, Germany; 2Department of Experimental Magnetic Resonance, Institute for Clinical Radiology, Muenster, Germany

The TurboCRAZED sequence is based on intermolecular multiple-quantum coherence (iMQC) detection. The provided contrast is weighted by tissue structure and this weighting can be adjusted by modifying one sequence parameter. We employed TurboCRAZED for the first time for stimulation-induced BOLD fMRI in animals. Electrical forepaw stimulation activated only a region in the primary sensory cortex as expected. Technical details of the sequence and the extensive animal monitoring used during the experiments will be discussed.