Abstract #2764

Triple-Layer Appearance of Human Cerebral Cortices on Phase-Difference Enhanced Imaging Using 3D Principle of Echo Shifting with a Train of Observations (PRESTO) Sequence

Tetsuya Yoneda¹, Toshinori Hirai², Yasuhiro Hiai¹, Hiroki Arimura¹, Yoko Kitajima³, Tomoyo Ideta⁴, Mika Kitajima², Yasuyuki Yamashita²

¹School of Health Sciences, Kumamoto University, Kumamoto, Japan; ²Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; ³Kumamoto Neurosurgery Hospital, Kumamoto, Japan; ⁴Saiseikai Kumamoto Hospital, Kumamoto, Japan

The laminar patterns in the human cerebral cortices have not been investigated at 3T MRI in living humans. We developed a novel technique of phase-difference enhanced (PADRE) imaging to enhance a phase difference of tissue structures. We evaluated axial 1-mm-thick PADRE images obtained using a 3T MR scanner in 6 healthy volunteers. We adjusted parameters of PADRE imaging using high-pass filter and phase enhancement techniques in order to enhance the laminar patterns of the cortices. In all 6 cases a triple-layer appearance was frequently seen in all bilateral primary motor, sensory, and visual cortices.