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Abstract #2876

MR ONCO-TREAT: a New Tool for Volumetric and Functional Analysis of Hepatic Tumors Monitored with Multi-Modal MRI

Mehmet Akif Gulsun1, Clifford Raabe Weiss2,3, Ralph Strecker3, Glenn Meredith1, Ihab R. Kamel2

1Imaging and Visualization, Siemens Corporate Research, Princeton, NJ, USA; 2The Russell H. Morgan Department of Radiology and Radiologic Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; 3MR Oncology, Siemens Healthcare, Erlangen, Germany

Multi-parametric MRI is becoming the gold standard for assessing hepatic tumor response to intra-arterial therapy. We present the MR-ONCO-TREAT software package for 3D evaluation of multi-parametric MR studies. The software includes: deformable image registration, interactive segmentation, and volumetric and functional analysis. In six patients with hepatocellular carcinoma, this software was able to register pre and post intra-arterial treatment MRI scans, segment tumor from surrounding liver, and provide volumetric and functional data analysis. On average, percent arterial enhancement decreased by 35.7, and the ADC increased by 9.5%. The MR-ONCO-TREAT software can automate the evaluation of hepatic tumors, possibly decreasing interpretive errors.