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Abstract #2912

Diffeomorphic Normalization Via Constant Acceleration Field

Yung-Chin Hsu1, Ching-Han Hsu1, Wen-Yih Isaac Tseng2

1Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan; 2Center for Optoelectronic Biomedicine and Department of Medical Imaging, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan

Image registration plays an important role in neuroimaging research. Under diffeomorphic framework, it is possible to solve the large-deformation problem usually encountered in image registration. Both Begs LDDMM and Ashburners constant velocity filed methods are diffeomorphic. We extended Ashburners method by using a constant acceleration filed. The result shows that LDDMM has shortest path length and lowest energy. Comparing our method and the constant velocity field method, the prior has lower energy and the later has shorter path length. The result suggests that these three methods might have their own strength and weakness in accuracy and computation cost.