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Abstract #3141

Microfabricated Magnetic Microparticles Enable High Contrast MRI Agents

Gary Zabow1,2, Stephen Dodd1, John Moreland2, Alan Koretsky1

1NINDS, NIH, Bethesda, MD, USA; 2Electromagnetics Division, NIST, Boulder, CO, USA

We demonstrate how top-down microfabrication can be used to micromachine magnetic resonance imaging contrast agents with more consistent, and higher, magnetic moments than commonly available chemical synthesized alternatives. Specifically, we describe the microfabrication of gold-coated nickel and iron micro-discs as T2* contrast agents and compare the contrast generated against traditional chemically synthesized MPIO's.