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Abstract #3262

qCBF: A Comparison of the Accuracy Between the Bookend Technique, Empirical Reference Values and [O15]-H20 PET in Moyamoya Patients

Vishal Parikh1, John Lee2, Wanyong Shin3, Jessy Mouannes1, Avi Snyder2, Colin Derdeyn2,4, Timothy Carroll1,5

1Biomedical Engineering, Northwestern University, Evanston, IL, USA; 2Radiology, Washington University, St. Louis, MO, USA; 3National Institute of Health, Baltimore, MD, USA; 4Neurology, Washington University, St. Louis, MO, USA; 5Radiology, Northwestern University, Chicago, IL, USA

We compared the accuracy of CBF measurements obtained by the Bookend Technique and CBF values rescaled to 22mL/100g/min for white matter. The accuracy with respect to [15O]-H2O positron emission tomography (PET) in patients with angiographically confirmed cerebrovascular disease. We found that the bookend approach provided a stronger correlation with the standard of reference PET values.