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Abstract #3282

The Measurement of Spatially-Dependant Tissue Sodium Concentration Increase in a Rodent MCAO Stroke Model

Friedrich Wetterling1, Sven Junge2, Arno Nauerth2, Oliviero Gobbo3, I. Mhairi Macrai4, Andrew J. Fagan1,5

1School of Physics, Trinity College Dublin, Dublin, Ireland; 2Bruker BioSpin, Ettlingen, Germany; 3Institute of Neuroscience, Trinity College, Dublin, Ireland; 4Glasgow Experimental MRI Centre, University of Glasgow, Glasgow, UK; 5Centre for Advanced Medical Imaging, St. Jamess Hospital, Dublin, Ireland

The aim of this study was to accurately quantify changes in the Tissue Sodium Concentration (TSC) in the acute phase of a rodent stroke model with high spatio-temporal resolution (0.38mm3/ 10min) at 7T.