Abstract #3282

The Measurement of Spatially-Dependant Tissue Sodium Concentration Increase in a Rodent MCAO Stroke Model

Friedrich Wetterling¹, Sven Junge², Arno Nauerth², Oliviero Gobbo³, I. Mhairi Macrai⁴, Andrew J. Fagan^1,5

¹School of Physics, Trinity College Dublin, Dublin, Ireland; ²Bruker BioSpin, Ettlingen, Germany; ³Institute of Neuroscience, Trinity College, Dublin, Ireland; ⁴Glasgow Experimental MRI Centre, University of Glasgow, Glasgow, UK; ⁵Centre for Advanced Medical Imaging, St. Jamess Hospital, Dublin, Ireland

The aim of this study was to accurately quantify changes in the Tissue Sodium Concentration (TSC) in the acute phase of a rodent stroke model with high spatio-temporal resolution (0.38mm3/ 10min) at 7T.