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Abstract #3333

Hemi-Parkinsons Disease Rat Model: Correlation Between Behaviour, Histology and MRI

Giuseppina Confalone1, Daniela Minchella1, Tiziana Florio1, Eugenio Scarnati1, Antonello Sotgiu2, Marcello Alecci2

1Dipartimento di Scienze e Tecnologie Biomediche, University of LAquila, LAquila, Italy; 2Dipartimento di Scienze della Salute, University of LAquila, LAquila, Italy

In this work we have developed a behavioural paradigm in a Hemi-PD rat model coupled with immuno-histological staining and MRI methods, to evaluate anatomical and physiological data. This Hemi-PD model in the rat should be useful to investigate difficulties raising in PD patients during the shifting from a mental set to another.