Abstract #3342

The Diagnostic Utility of Susceptibility Weighted Imaging (SWI) in Amyotrophic Lateral Sclerosis.

Akiko Jingu¹, Makoto Amanuma¹, Keigo Endou²

¹Diagnostic Radiology, Gunma University Hospital, Maebashi-shi, Gunma, Japan; ²Diagnostic Radiology, Gunma University Hospital, Japan

To evaluate the susceptibility weighted images (SWI) for diagnosis of amyotrophic lateral sclerosis (ALS) and determine whether the low signal intensity of precentral gyral cortex on T2WI is due to susceptibility effect. Nine patients with ALS and thirty control subjects were studied. On SWI, all ALS patients showed decreased signal intensity of precentral gyral cortices and gray matter-white matter contrast ratio was significantly higher than that of non ALS patients (p<0.001).