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Abstract #3487

Nonenhanced Time-Resolved MRA Using Inflow Arterial Spin Labeling

Shinichi Kitane1, Tokunori Kimura1, Yuichi Yamashita2, Mitsue Miyazaki3

1MRI development department, Toshiba Medical Systems Corp., Otawara, Tochigi, Japan; 2MRI marketting department, Toshiba Medical Systems Corp., Tokyo, Japan; 3Advanced Clinical Research, MR, Toshiba Medical Research Institute USA, Inc, Vernon Hills, IL, USA

A new nonenhanced time-resolved MRA technique was proposed using inflow arterial spin labeling (ASL) with multiple non-slice selective IR pulses for suppressing background tissue signals. After saturating imaging slab, two mIR pulses tuned for nulling of brain tissues were applied, and imaging with 3D-SSFP sequence was performed on 1.5T MRI for normal volunteer brain. The stationary signal in brain tissue, gray-matter, white-matter, and CSF were well suppressed. Peripheral blood vessels were well visualized with increasing TI. Although further optimization of parameters is required, this method is promising approach for non-contrast dynamic MRA.