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Abstract #3493

Sodium MRI of Core and Penumbra in Ischemic Stroke Patients

Adrian Tsang1, Rob Stobbe1, Ken Butcher2, Shazam Hussain, Yusuf Bhagat1, Derek Emery3, Christian Beaulieu1

1Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada; 2Neurology, University of Alberta, Edmonton, Alberta, Canada; 3Radiology, University of Alberta, Edmonton, Alberta, Canada


Sodium imaging may complement both diffusion- and perfusion-weighted proton imaging in the assessment of ischemic stroke patients. The purpose of this study is to evaluate the relative tissue sodium intensity in the penumbra defined by PWI-DWI mismatch and core infarct regions defined by DWI from acute to subacute times. Preliminary results based on 4 longitudinal subjects demonstrated that mean relative sodium intensity increases with time only in the infarct core but does not change in the penumbra.

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