Robust Diffusion-Weighted Imaging Using Split-Blade PROPELLER and LRX Phase Modulation

Zhiqiang Li¹, Xiaoli Zhao¹, Donglai Huo², James Pipe², Patrick Le Roux³

To address the non-CPMG condition, diffusion-weighted (DW) PROPELLER uses an XY2 phase modulation. However, it still has some constraints such as high refocusing flip angle, limited echo train length, high SAR and sensitivity to dielectric effect at 3T. A quadratic phase modulation strategy was proposed by Le Roux allowing the use of low flip angle and long echo train with SSFSE, but requires double encoding. We adapted this novel strategy in DW-PROPELLER with the split blade method, producing more stable signal with less decay. In vivo images demonstrate the advantages of this new technique.