Abstract #3545

Dataset-Independent Reconstruction of High Angular Resolution Diffusion Sampling Schemes by Generalized Q-Space Imaging

Fang-Cheng Yeh¹, Van Jay Wedeen², Wen-Yih Isaac Tseng^1,3

¹Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan; ²MGH Martinos Center for Biomedical Imaging, Harvard Medical School, Charlestown, MA, USA; ³Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan

We propose a novel q-space imaging method derived from the Fourier transform relationship between the MR signals and diffusion displacement probability density function. The method is featured by being independent of the q-space sampling schemes, such as high angular resolution images (HARDIs) and diffusion spectrum imaging (DSI) grid dataset. The accuracy of the method is examined in comparison with q-ball imaging (QBI) and DSI.