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Abstract #3624

Assessment of Blood-Brain Water Transfer by Arterial Spin Labeling Based T2 Measurements

Johannes Gregori1, Matthias Gnther2, Norbert Schuff3,4

1Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA; 2Neurology, University Hospital Mannheim, University of Heidelberg, Heidelberg, Germany; 3Radiology & Biomedical Imaging, University of California San Francsico, CA, USA; 4Center for Imaging of Neurodegenerate Diseases, CIND, VA Medical Center, San Francisco

The assessment of water transfer from vasculature to brain tissue has been difficult with T1 based Arterial Spin Labeling (ASL). In this work, by acquiring multiple echo times in ASL measurements, we demonstrate the feasibility of T2 dependent ASL to assess blood water transfer.