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Abstract #3637

Investigating Transcranial Magnetic Stimulation (TMS) Effects Using Pulsed Arterial Spin Labeling (PASL)

Andrea Federspiel1, Ariane Orosz1, Kay Jann1, Matthias Grieder1, Miranka Wirth1, Roland Wiest2, Thomas Dierks1

1Dept. of Psychiatric Neurophysiology, University Hospital of Psychiatry, Bern, Switzerland; 2Dept. of Neuroradiology, University Hospital/Inselspital, Bern, Switzerland

Here we investigate transcranial magnetic stimulation (TMS) effects using Pulsed Arterial Spin Labeling (PASL) on healthy subjects. We addressed the question of whether an effect of TMS is detectable with ASL in subject performing a task. We aimed to explore putative TMS effects on CBF measure. We observe a reduction of CBF measure post TMS as compared to pre TMS condition only in brain regions that were subject to TMS stimulation including its homologue contralateral, not stimulated side. Although the small sample size, our data demonstrate the feasibility of detecting TMS effects using ASL.