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Abstract #3644

Cerebral Blood Flow and Transit Time Measured by Quantitative Arterial Spin Labeling: Comparison with 15O-PET

Hironori Kamano1, Takashi Yoshiura1, Akio Hiwatashi1, Koji Yamashita1, Eiki Nagao1, Yukihisa Takayama1, Tomoyuki Noguchi1, Koichiro Abe1, Koichiro Kaneko1, Ivan Zimine2, Tomoyuki Okuaki2, Hiroshi Honda1

1Department of Clinical Radiology, Kyushu University, Fukuoka, Japan; 2Philips Electronics Japan, Japan


We compared CBF and arterial transit time (ATT) measured by ASL with CBF and mean transit time (MTT) measured by 15O-PET in 13 patients with cerebral arterial steno-occlusive diseases. Region-of-interest analysis of the parametric maps revealed a significant correlation between CBF values by ASL and those by PET. Comparison of ATT by ASL and MTT by PET revealed no significant correlation, while left-to-right ratio (L/R) of ATT in posterior watershed area significantly correlated with L/R of MCA CBF and L/R of MCA MTT by PET. ATT by ASL may convey clinically useful information regarding regional hemodynamic status.

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