Cerebral Blood Flow and Transit Time Measured by Quantitative Arterial Spin Labeling: Comparison with 15O-PET

Hironori Kamano¹, Takashi Yoshiura¹, Akio Hiwatashi¹, Koji Yamashita¹, Eiki Nagao¹, Yukihisa Takayama¹, Tomoyuki Noguchi¹, Koichiro Abe¹, Koichiro Kaneko¹, Ivan Zimine², Tomoyuki Okuaki², Hiroshi Honda¹

We compared CBF and arterial transit time (ATT) measured by ASL with CBF and mean transit time (MTT) measured by 15O-PET in 13 patients with cerebral arterial steno-occlusive diseases. Region-of-interest analysis of the parametric maps revealed a significant correlation between CBF values by ASL and those by PET. Comparison of ATT by ASL and MTT by PET revealed no significant correlation, while left-to-right ratio (L/R) of ATT in posterior watershed area significantly correlated with L/R of MCA CBF and L/R of MCA MTT by PET. ATT by ASL may convey clinically useful information regarding regional hemodynamic status.