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Abstract #3756

Single-Breathhold Myocardial T2 and T2* Quantification in Normal Volunteer Subjects at 3T

Hua Guo1,2, Jerry S. Cheung1,2, Daniel Kim3, Pek-Lan Khong4, Gary M. Brittenham5, Ed X. Wu1,2

1Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong, China; 2Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong, China; 3Department of Radiology, New York University School of Medicine, New York, USA; 4Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong; 5Department of Pediatrics and Medicine, Columbia University College of Physicians and Surgeons, New York, USA

Increased B0 and B1 inhomogeneity, together with increased motion artifacts, present challenges for cardiac imaging and quantitation at 3T. This study measured myocardial T2 in normal subjects at 3T using a novel single-breathhold black-blood hybrid TSE/MESE T2 measurement protocol. The average myocardial T2 was found to be 39.67.4ms, with peak-to-peak variations of the measured T2 values < 5%. The results demonstrate the feasibility of myocardial T2 quantitation at 3T.