Abstract #3794

Time-Resolved MR Angiography of the Distal Lower Extremities: Clinical Application, Vessel Diameters, and Contrast Dynamics

Gurpreet Singh Sandhu^1,2, Rod P. Rezaee³, Jeffrey L. Duerk^1,4, Mark A. Griswold^1,4, Vikas Gulani^1,2

¹Department of Radiology, University Hospitals of Cleveland, Cleveland, OH, USA; ²Case Center for Imaging Research, Case Western Reserve University, Cleveland, OH, USA; ³Department of Otolaryngology-Head and Neck Surgery, University Hospitals of Cleveland, Cleveland, OH, USA; ⁴Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA

Bolus-chase contrast enhanced MR angiography (ceMRA) of the distal leg does not provide dynamic information about arterial blood flow and suffers from limitations such as missed boluses and venous contamination. Here, application of dynamic contrast-enhanced MR angiography using time resolved imaging with stochastic trajectories (TWIST) for arteriography of the distal leg is described and a quantitative analysis of contrast dynamics of lower legs is performed. A quantitative comparison of apparent arterial lumen diameters in dynamic images obtained with the TWIST method and images acquired with a ceMRA method is also performed.