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Abstract #3807

Changes in Longitudinal and Radial Strain After Coronary Embolization Detected on Velocity Encoded Phase Contrast Magnetic Resonance Imaging

Marcus Carlsson1,2, Demetrius Dicks1, Einar Heiberg2, Alastair Martin1, David Saloner1, Hakan Arheden2, Maythem Saeed1

1UCSF, Dep of Radiology and Biomedical Imaging, San Francisco, CA, USA; 2Lund University Hospital, Dep of Clinical Physiology, Lund, Sweden

This MRI study determined the ability of phase velocity encoded (PC-MR) strain to detect the functional effects on left ventricular radial and longitudinal strain after microembolization in the LAD coronary artery in an animal model. PC-MR imaging was sensitive to dectect the changes in longitudinal and radial strain after selective LAD coronary embolization. Longitudinal strain of the patchy microinfarction declined from baseline to 1-hour after embolization, a decline that persisted at 1 week. Radial strain declined acutely 1-hour after LAD embolization and worsened at 1 week post-embolization.