Chun Xu1, Kevin Koomalsingh1, Aaron S. Blom1, Larry Dougherty2, Gamaliel Isaac2, Joseph H. Gorman1, Robert C. Gorman1, James J. Pilla1,2
1Surgery Department, Hospital of University of Pennsylvania, Philadelphia, PA, USA; 2Radiology, University of Pennsylvania, Philadelphia, PA, USA
This study presents a novel method to accurately quantify transmural deformation in the left ventricle. A special pulse sequence was developed that applied the optimized SPAMM tag pulse in three distinct planes in one acquisition. Displacements of pixels were tracked using an optimized 3D optical flow method, and used to compute systolic principal strain magnitude and orientation. Minimal user interface were required and results are in agreement with previous reported data, but with sufficient resolution for transmural LV strain evaluation.