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Abstract #3840

Phantom Investigation on the Accuracy of Different Pulse Sequences for the Determination of Arterial Distensibility

Valentina Taviani1,2, Andrew James Patterson1, Pauline Wong1, Michael P. Sutcliffe2, Martin John Graves1, Jonathan Harvey Gillard1

1Department of Radiology, University of Cambridge, Cambridge, UK; 2Department of Engineering, University of Cambridge, Cambridge, UK

The distensibility coefficient, often used as an index of arterial elasticity, requires the maximum relative change in the luminal cross-sectional area to be determined. In this work a human-tissue-mimicking phantom was imaged using three different pulse sequences (cine phase-contrast, cine bright-blood and a custom-developed cine black-blood using spatial saturation bands). The results were compared with high resolution digital photography (HRDP) assumed to be the gold-standard. Cine black-blood best agreed with HRDP (rms deviation = 0.011mm) with cine phase data the worst (rms deviation = 0.113mm) resulting in a 26% underestimation of the distensibility coefficient compared to black-blood.