Abstract #3846

Dynamic Contrast-Enhanced MRI Detects Progression of Inflammation in a Rabbit Model of Atherosclerosis

William Sean Kerwin¹, Jerry Ricks², Michael Rosenfeld²

¹Radiology, University of Washington, Seattle, WA, USA; ²Pathology, University of Washington, Seattle, WA, USA

This study investiated the association of dynamic contrast-enhanced MRI measurements with macrophage content in experimental lesions of atherosclerosis at different time points in a rabbit model. We found a progressive increase that showed significant correlation with a corresponding increase in macrophage content.