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Abstract #3865

Time-Resolved MR Angiography in Evaluation and Mapping of Central Thoracic Veno-Occlusive Disease

Kambiz Nael1, Stefan G. Ruehm1, Mayil Krishnam1, Gerhad Laub2, J Paul Finn1

1Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Siemens, Los Angeles, CA, USA

Using time-resolved angiography with interleaved stochastic trajectories (TWIST) and parallel acquisition can improve the performance of time-resolved MRA. Our results demonstrate that TR-MRA with a high comparable sensitivity, and need for only a small gadolinium dose (6ml), has the potential to be used as an initial and screening diagnostic tool in assessment of central venous occlusive disease, obviating the need for conventional MRA and higher contrast dose in normal or near-normal examination. However, due to relatively lower specificity of TR-MRA, adjunct use of conventional CE-MRA is still required for accurate grading of venous occlusive disease.