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Abstract #3867

Leading Edge Fidelity in View-Shared Time-Resolved 3D MRA

Petrice Marie Mostardi1, Clifton Haider1, Philip Rossman1, Stephen Riederer1

1Mayo Clinic, Rochester, MN, USA

Artifactual signal enhancement in a vessel occurring in advance of actual contrast arrival can misrepresent the underlying contrast bolus dynamics. The purpose of this work is to show how the anticipation artifact occurring in advance of the contrast bolus leading edge can be minimized with appropriate ordering of phase encoding views. This is demonstrated experimentally in phantoms and with in vivo CE-MRA. Reconstructing time-resolved data sets using predominantly high spatial frequency data acquired before the central k-space region for that update allows for decreased anticipation artifact and more accurate depiction of the contrast bolus leading edge.