Aoife N. Keeling1, Ravi K. Singh1, Cormac Farrelly1, Hyun Jeong2, Ty A. Cashen3, John Sheehan1, James C. Carr1, Timothy J. Carroll4
1Dept of Cardiovascular Imaging, Northwestern Memorial Hospital, Chicago, IL, USA; 2Dept of Biomedical Engineering, Northwestern Memorial Hospital, Chicago, IL, USA; 3Dept of Biomedical Engineering, Northwestern Memorial Hospital, Chicago, Ilinois, USA; 4Dept of Cardiovascular Imaging, Dept of Biomedical Engineering, Northwestern Memorial Hospital, Chicago, IL, USA
Time-resolved contrast enhanced magnetic resonance angiography, can provide arterial anatomical and pathological detail, but can also follow the first pass of contrast through visceral parenchymal tissue in order to evaluate vascular flow dynamics or perfusion. We hypothesize that dynamic mask-mode subtraction yields perfusion weighted images of the renal parenchyma with a single doe of Gadolinium. Eleven healthy volunteers and one renal transplant patient were recruited to undergo MRI examination using a radial three-dimensional FLASH acquisition with sliding window view-share reconstruction on a 1.5T Siemens MRI scanner. The technique produced diagnostic quality angiographic images and perfusion maps in all.