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Abstract #3918

Late Gadolinium Enhancement in Apparently Unenhanced Myocardium in Dilated Cardiomyopathy; Evaluation Using Myocardium to Lumen Ratio

Atsushi Kono1, Naoaki Yamada1, Teruo Noguchi2, Tadashi Watabe1, Yoko Masukata2, Yoshiro Hori1, Suzu Kanzaki1, Masahiro Higashi1, Hiroaki Naito1

1Department of Radiology and Nuclear Medicine, National Cardiovascular Center, Suita, Osaka, Japan; 2Division of Cardiology, National Cardiovascular Center, Suita, Osaka, Japan

We quantified myocardium-to-lumen signal ratio (M/L) to detect abnormality of apparently non-enhanced myocardium in dilated cardyomyopathy (DCM). We determined variability of normal M/L depending upon time after contrast injection and subject conditions such as heart rate and renal function, and evaluated M/L of DCM without apparent LGE. In the results, normal M/L was almost invariable in time between 2 to 20 minutes after gadolinium administration, and almost invariable depending upon subject conditions. M/L of DCM was significantly higher than M/L of normal myocardium. Higher M/L of DCM suggests increased interstitial tissue due to fibrosis and myocyte atrophy in DCM.