Abstract #3965

Accelerated MR Protocol for Cartilage Volume Analysis and Whole-Organ Joint Assessment for Osteoarthritis Research Studies

Vaishali Soneji Lafita¹, Richard Kijowski¹, David Rabago², Michael Woods¹, Dana Tudorascu³, Jessica Klaers⁴, Walter Block^4,5

¹Radiology, University of Wisconsin, Madison, WI, USA; ²Family Medicine, University of Wisconsin, Madison, WI, USA; ³Statistics, University of Wisconsin, Madison, WI, USA; ⁴Medical Physics, University of Wisconsin, Madison, WI, USA; ⁵Biomedical Engineering , University of Wisconsin, Madison, WI, USA

This study was performed to determine whether an 8 minute accelerated MR protocol consisting of isotropic resolution VIPR-SSFP and sagittal fat-suppressed T2-weighted FSE sequences could be used to provide rapid cartilage volume analysis and whole-organ joint assessment for osteoarthritis research studies. Cartilage volume measurements and whole-organ joint assessment using the WORM system were performed on 20 patients enrolled in an osteoarthritis research study using a 20 minute standard MR protocol and the accelerated MR protocol. There was a small mean difference of 0.27cm3 between cartilage volume measurements and strong correlation between WORM scores obtained using the standard and accelerated protocols.