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Abstract #3983

In Vitro Correlation of MR Parameters Under Loading with Biomechanical Properties of Degenerated Articular Cartilage

Vladimir Juras1,2, Pavol Szomolanyi1,2, Zuzana Majdisova1,2, Irene Sulzbacher3, Stefan Gbler4, Siegfried Trattnig1

1MR Centre / Highfield MR, Medical University of Vienna, Vienna, Austria; 2Department of Imaging Methods, Institute of Measurement Science, Bratislava, Slovakia; 3Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria; 4Inst. of Materials Science and Technology, TU Wien, Vienna, Austria

The purpose of this study was to compare MR parameters under loading with biomechanical properties of cartilage measured by indentation tests to show that the impact of biochemical changes in degenerated cartilage can be predicted by noninvasive imaging approach (MRI). In some cases, the correlation between MR and selected biomechanical parameters were relatively high, in particular T1 showed strong relation to the biomechanical parameters (T1 vs instantaneous modulus, r = 0.6324).