Abstract #3983

In Vitro Correlation of MR Parameters Under Loading with Biomechanical Properties of Degenerated Articular Cartilage

Vladimir Juras^1,2, Pavol Szomolanyi^1,2, Zuzana Majdisova^1,2, Irene Sulzbacher³, Stefan Gbler⁴, Siegfried Trattnig¹

¹MR Centre / Highfield MR, Medical University of Vienna, Vienna, Austria; ²Department of Imaging Methods, Institute of Measurement Science, Bratislava, Slovakia; ³Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria; ⁴Inst. of Materials Science and Technology, TU Wien, Vienna, Austria

The purpose of this study was to compare MR parameters under loading with biomechanical properties of cartilage measured by indentation tests to show that the impact of biochemical changes in degenerated cartilage can be predicted by noninvasive imaging approach (MRI). In some cases, the correlation between MR and selected biomechanical parameters were relatively high, in particular T1 showed strong relation to the biomechanical parameters (T1 vs instantaneous modulus, r = 0.6324).