Meeting Banner
Abstract #4089

Simultaneous R2* and Fat Fraction Determination of the Liver with Modulus and Real Multiple Gradient-Echo MRI

Naoki Ohno1, Tosiaki Miyati1, Eri Ono1, Harumasa Kasai2, Masaki Hara2, Yuta Shibamoto2, Makoto Kawano2, Miyuki Asahi2, Tomoyuki Okuaki3, Tomoyuki Yamamoto4

1Kanazawa University, Kanazawa, Japan; 2Nagoya City University Hospital, Nagoya, Japan; 3Philips Electronics Japan, Tokyo, Japan; 4Kanazawa University Hospital, Kanazawa, Japan

To evaluate the liver metabolism, T2*-IDEAL is useful for assessment when there is co-occurrence of hepatic steatosis and iron deposition, but this method is not necessarily implemented in standard MR imagers. Thus, we devised a method for analyzing R2* (iron content), and fat fraction of the liver tissue simultaneously using modulus and real multiple gradient-echo (MRM-GRE) sequence. The MRM-GRE method makes it possible to simply and accurately assess the fat content and the iron content. The ability to obtain both of them at the same time allows us to optimize the advantages of each and thereby obtain more information about the liver metabolism.