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Abstract #4093

Single Breath Hold Multi-Echo Liver Fat Quantitation

Marko K. Ivancevic1,2, Jouke Smink3, Hero K. Hussain2, Thomas L. Chenevert2

1MRI, Philips Medical Systems, Cleveland, OH, USA; 2Radiology, University of Michigan, Ann Arbor, MI, USA; 3MRI, Philips Medical Systems, Best, Netherlands


Magnetic resonance imaging and spectroscopy provide a tool for fat quantitation for a wide range of liver conditions such as steatosis, non alcoholic fatty liver disease (NAFL), or non alcoholic steatohepatitis (NASH). Various methods are being used for fat quantitation, such as MR spectroscopy or 3-point Dixon. A practical method based on dual flip angle, in-phase and out-of-phase echoes and T2* correction has been developed. Here we present an improvement of the method, where we acquired 6 echoes (3 in-phase/out-of-phase pairs) with 2 flip angles providing fat quantitation and T2* correction in a single breath hold scan.