Abstract #4114

Assessing Native and Transplant Kidneys with Diffusion Weighted MR Imaging: Mean Vs Delta ADC

Robert W. Garrett¹, Karl Vigen¹, Sean Fain², Garima Agrawal¹, Thomas Grist¹, Elizabeth A. Sadowski¹

¹Department of Radiology, University of Wisconsin, Madison, WI, USA; ²Department of Medical Physics, University of Wisconsin, Madison, WI, USA

The purpose of our study was to evaluate the mean cortical and medullary ADC values in both native and transplant kidneys with normal function versus diminished function, and determine the utility of using the corticomedullary ADC difference (delta ADC) to differentiate between these groups. A decrease in delta ADC was noted between the normal and diminished functioning natives and the normal and diminished functioning transplants, however statistical significance was present only in the native kidney group. The delta ADC value is a novel technique which, along with mean medullary and cortical ADC values, may differentiate kidneys based on function.