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Abstract #4171

Study of Regression of Breast Tumor in Mice Model Using MRI

Sanjay Annarao1, Preeti Singh2, Madan Madav Godbole2, Raja Roy1, C L. Khetrapal1

1Centre of Biomedical Magnetic Resonance, Lucknow, Uttar Pradesh, India; 2Department of Endocrinology, Sanjay Gandhi Post-graduate Institute of Medical Sciences, Lucknow, UttarPradesh, India

Therapeutic efficacy of the drug Chloroquine in breast tumor in mice model has been studied and the results are presented. The MRI studies involved examining the response of two different types of treatments, namely (a) oral administration of molecular Iodine and (b) molecular Iodine with chloroquine. The results indicate more decrease of the tumor size in combined treatment compare to the molecular iodine alone. Therefore, chloroquine in combination with molecular iodine appears to be a better as therapeutic efficacy as pointed out in-vitro studies.