Meeting Banner
Abstract #4182

Prostate DCE-MRI with a 16-Channel Surface Array and Endorectal Coil Using Slice Oversampling and SENSE to Minimize Blood Inflow Effect

Marcelino Bernardo1,2, Yuxi Pang3,4, Baris Turkbey2, Raphael Alford2, Vijay Shah2, Ahmed M. Gharib5, Peter Choyke2

1Imaging Physics, SAIC-Frederick, Inc., Frederick, MD, USA; 2Molecular Imaging Program, National Cancer Institute, Bethesda, MD, USA; 3Philips Medical Systems, Cleveland, OH, USA; 4Molecular Imaging Program,, National Cancer Institute, Bethesda, MD, USA; 5NIDDK, Bethesda, MD, USA

To overcome blood inflow effect in accurately determining the arterial input function from the femoral artery in prostate DCE-MRI, we have performed a preliminary study on two patients to evaluate four-fold slice oversampling with SENSE using the 16-channel anterior half of a 32-channel cardiac array in combination with an endorectal coil. The thicker excitation slab provides for a more accurate determination of the contrast agent concentration in the blood which should provide for more consistent pharmacokinetic parameters across patients but there is a factor of two loss in temporal resolution. The addition of the posterior half and a dual element endorectal coil should improve SENSE performance.