Abstract #4218

Comparison of Blood Flow Measurements Using 2-Compartment Model and Deconvolution Based Analysis of T1-Weighted DCE MRI of Breast Tumors

Smitha Makkat¹, Robert Luypaert¹, Johan De Mey¹, Steven Sourbron²

¹Radiology/BEFY, Vrije Universiteit Brussel, Brussels, Belgium; ²Radiology, University Munich - Grosshadern Hospital, Munich, Germany

An accurate assessment of the Tumor Blood Flow can become crucial in deciding the best management for breast cancer patients. In this study, the aim is to compare the model-free blood flow values derived with deconvolution analysis against those derived with a 2-compartment uptake model. Model-free and model based tumor blood flow are well-correlated, but there is a systematic difference in the values obtained.