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Abstract #4324

Bo Anchored Spatial Excitation for Spectroscopic Imaging Under Field Inhomogeneity

Arnaud Guidon1, Allen W. Song1

1Brain Imaging and Analysis Center, Duke University, Durham, NC, USA

In this work, we present a new method aimed at achieving robust spectroscopic metabolite imaging in the presence of inhomogeneous magnetic fields. This technique is based on a new excitation strategy termed Bo anchor spatial excitation (BASE), which could take advantage of the recent advances in parallel transmission to achieve a region-specific, frequency-matched excitation. In particular, we show that BASE can help recover spectral resolution in regions where field heterogeneity would otherwise lead to severe off-resonance and dispersion effects. We anticipate that this method will find broad applications leading to more effective whole-brain spectroscopic imaging in vivo.