Quantitative Analysis of Pulmonary Perfusion Using First Pass Perfusion Magnetic Resonance Imaging

Jie J. Cao¹, Yi Wang^1,2, William Schapiro¹, Jeannette McLaughlin¹, Joshua Cheng¹, Michael Passick¹, Nathaniel Reichek^1,2

Many pulmonary diseases affect pulmonary vasculature whether primarily or secondarily. In patients with advanced primary pulmonary hypertension pulmonary perfusion is marked reduced. Therefore quantitative pulmonary perfusion may be clinically useful in diagnosing pulmonary vascular abnormalities. In this study we investigated 2D dynamic contrast-enhanced magnetic resonance imaging (MRI) using a saturation recovery SSFP sequence to quantitatively analyze pulmonary perfusion in normal volunteers.