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Abstract #4425

MR-Guided Thermal Ablation in Bone Using a Rapid Chemical Shift Imaging Technique

Brian A. Taylor1, Andrew M. Elliott1, John D. Hazle1, Roger Jason Stafford1

1Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

The rapid CSI technique is presented that can provide measurements of temperature in bone marrow at high spatiotemporal resolutions where CPD techniques are currently limited due to intravoxel lipid contamination. The technique allows a rapid acquisition without time or SNR-consuming lipid suppression and preserves the lipid signal for internal correction. Temperature calibrations seen in this study are consistent with those seen in lipid-containing materials. The ability of monitoring more than one lipid peak at high spatiotemporal resolution is demonstrated.