Tomoka Kurita1,2, Kagayaki Kuroda3,4, Takeo Ohsaka1
1Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Midori-ku, Yokohama, Japan; 2R & D Center, Terumo Corporation, Ashigarakami-gun, Kanagawa, Japan; 3Department of Human and Information Sciences, School of Information Science and Technology, Tokai University, Hiratsuka, Kanagawa, Japan; 4Medical Device Development Center, Foundation for Biomedical Research and Innovation, Chuo-ku, Kobe, Japan
For MR-guided endovascular procedures, the passive visualization technique of guidewires and catheters with the coating of the Gd-DTPA based polymer was developed. The guidewire and urethane tube were coated using the polymer by a dipping process and they were soaked into saline for swelling. Imaging was performed using a clinical 1.5 Tesla MRI with T1-FLAIR and FSPGR sequence. Coating devices were visible with a high signal intensity without any susceptibility artifact. The signal enhancement was maintainable and repeatable. This study shows that the MR-visible catheters and guidewires coated with the Gd-DTPA based polymer will contribute to the development of MR-guided endovascular procedures.