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Abstract #4436

A Gd-DTPA Based Insoluble Polymer Coating Technique for Endovascular Device Visualization

Tomoka Kurita1,2, Kagayaki Kuroda3,4, Takeo Ohsaka1

1Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Midori-ku, Yokohama, Japan; 2R & D Center, Terumo Corporation, Ashigarakami-gun, Kanagawa, Japan; 3Department of Human and Information Sciences, School of Information Science and Technology, Tokai University, Hiratsuka, Kanagawa, Japan; 4Medical Device Development Center, Foundation for Biomedical Research and Innovation, Chuo-ku, Kobe, Japan

For MR-guided endovascular procedures, the passive visualization technique of guidewires and catheters with the coating of the Gd-DTPA based polymer was developed. The guidewire and urethane tube were coated using the polymer by a dipping process and they were soaked into saline for swelling. Imaging was performed using a clinical 1.5 Tesla MRI with T1-FLAIR and FSPGR sequence. Coating devices were visible with a high signal intensity without any susceptibility artifact. The signal enhancement was maintainable and repeatable. This study shows that the MR-visible catheters and guidewires coated with the Gd-DTPA based polymer will contribute to the development of MR-guided endovascular procedures.