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Abstract #4459

Dependence of Blood R2 Relaxation Rate on Echo Spacing Using a CPMG Sequence at 7T

Alexander Graeme Gardener1, Susan Tracy Francis1, Penny Anne Gowland1

1Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK

The dependence of measured in-vitro blood R2 relaxation rate on sequence parameters and sample oxygenation and haematocrit was investigated at 7T using a multi-echo CPMG sequence. Results show that as inter-echo spacing increases, measured R2 rates increase, with low oxygenation and high haematocrit blood samples showing the largest enhancement. Pure plasma showed little dependency on inter-echo spacing as expected. Results for fitting blood R2,0 components at 7T are presented, and compared to previous literature studies at lower field strengths.