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Abstract #4528

MR Contrast Generated by Altering Parameters of Adiabatic Pulses: Theoretical Simulations and in Vivo MRS Results

Silvia Mangia1, Timo Liimatainen1, Michael Garwood1, Pierre-Gilles Henry1, Shalom Michaeli1

1CMRR, Dept. of Radiology, University of Minnesota, Minneapolis, MN, USA

Rotating frame relaxation rates are measured during radiofrequency (RF) irradiation, and therefore can be altered by choosing different RF settings. The present work focuses on rotating frame relaxation methods based on adiabatic pulses, exploring how MR contrast can be created by using different pulse modulation functions, maximum amplitude or bandwidth of the adiabatic pulse. Results from theoretical simulations and animal MRS experiments are presented.