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Abstract #4573

Automatic Regularization for Magnetic Resonance Inverse Imaging

Aapo Nummenmaa1, Matti S. Hamalainen1, Fa-Hsuan Lin1,2

1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 2Institute for Biomedical Engineering, National Taiwan University, Taipei, 106, Taiwan

We propose a simple method for automatic regularization of dynamic magnetic resonance Inverse Imaging (InI). Regularization is interpreted in a Bayesian way, as a variance parameter of a Gaussian prior, and marginal likelihood is used to estimate these parameters. The proposed method is compared to the presently used ad hoc regularization of InI by using empirical data from a visual stimulation experiment. Possible extension of the method for dynamic modeling of the regularization parameters is discussed.