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Abstract #4611

19F/1H Simultaneous 3D Radial Imaging of Atherosclerotic Rabbits Using Self-Navigated Respiratory Motion Compensation

Jrgen Rahmer1, Jochen Keupp1, Shelton D. Caruthers2,3, Oliver Lips1, Todd A. Williams3, Samuel A. Wickline3, Gregory M. Lanza3

1Philips Research Europe, Hamburg, Germany; 2Philips Healthcare, Andover, MA, USA; 3Washington University, St. Louis, MO, USA

MR molecular imaging of low doses of tracer material often requires long scan times and makes motion compensation strategies desirable. 3D radial imaging with golden section profile interleaving allows auto-navigated motion compensation. Here, it is applied to simultaneous 19F/1H imaging of the aorta of atherosclerotic rabbits after systemic administration of 19F-based angiogenesis-targeted nanoparticles. Tracking of respiratory motion is