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Abstract #4622

3-D Prospective Motion Correction for MR Spectroscopy

Brian Keating1, J C. Roddey2, Weiran Deng1, Anders Dale2, Nathan White3, V Andrew Stenger1, Thomas Ernst1

1Dept. of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA; 2Dept. of Neurosciences, University of California at San Diego, La Jolla, CA, USA; 3Cognitive Science, University of California at San Diego, La Jolla, CA, USA

Patient motion during MR spectroscopy (MRS) acquisitions compromises the spectral quality. Therefore, we adapted a 3D image-based prospective motion correction module for use with a 1H PRESS sequence. A spiral navigator is acquired immediately prior to the MRS water suppression module, to obtain three orthogonal images from which head motion is estimated. By applying the appropriate rotations and translations, the voxel can be made to remain stationary with respect to the brain. Spectra acquired during head motion demonstrate improved spectral quality, including a reduction in lipid contamination, lower line width, and spectral reproducibility, when motion correction is applied.