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Abstract #4646

Real-Time Motion Corrected MRS Using EPI Navigators

Aaron T. Hess1, Matthew Dylan Tisdall2,3, Ernesta M. Meintjes1, Andre J. W. van der Kouwe2,3

1Human Biology, University of Cape Town, Cape Town, South Africa; 2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 3Department of Radiology, Harvard Medical School, Brookline, MA, USA

In this abstract we present a real-time motion navigation technique for MRS. The technique uses a low resolution echo planar imaged (EPI) volume acquisition (duration < 500ms), inserted in the relaxation time of each TR before the spectroscopy excitation. The EPI images are processed online and co-registered using PACE in order to provide real-time feedback to adjust the imaging coordinate system for rigid body translation and rotation. Our results demonstrate this technique can be incorporated into single voxel spectroscopy without increasing acquisition duration or impacting on the spectral quality.