Depiction of SPIO in Atherosclerotic Plaque Using True Resolution SGM

Gopal Varma¹, Marcus Richard Makowski¹, Hannes Dahnke², Stephen Keevil³, Rene M. Botnar¹, Tobias Schaeffter¹

Detection of atherosclerotic plaque with iron oxide contrast agents that induce a susceptibility effect in MRI is sometimes hindered by competing sources of negative contrast. Although positive contrast techniques aid in detection, hyper-intensities are often over-emphasised and may thus fail to accurately depict the plaque. We present a true resolution positive contrast method post-processing that provides a more accurate depiction of e.g. SPIO induced susceptibility effect with relation to its source.