Harry Robert Marshall1,2, Robert Z. Stodilka1,2, Benoit Lewden1, Jean Theberge1,2, Eric Sabondjian1,2, Alexandre Legros1, Andrea Mitchell1, Lela Dorrington1, Jane Sykes1, Frank S. Prato1
1Imaging, Lawson Health Research Institute, London, ON, Canada; 2Medical Biophysics, The University of Western Ontario, London, ON, Canada
Attenuation correction is necessary to generate quantitatively accurate PET images but it is not straightforward in PET/MR hybrid imaging. One method to generate an attenuation map under such circumstances is to segment the MR images into tissue types and to assign said tissue types their known attenuation coefficients. The aim of our study was to determine whether using multispectral MR is beneficial to this end, and if so, which combination of pulse sequences is most effective. We confirmed that multispectral MR yields superior attenuation maps than single MR data sets, but the best combination of sequences depends upon anatomical position.