Allen W. Song1, Nan-Kuei Chen1, Brian Soher2
1Brain Imaging and Analysis Center, Duke
University, Durham, NC, USA; 2Radiology, Duke University, Durham,
In this report we aim to achieve a uniform and targeted spatial excitation under Bo inhomogeneity. Specifically, we use fat suppression as an example to demonstrate a new strategy termed Bo anchored spatial excitation (BASE), where the transmit frequencies of individual channels are matched to those of the local regions under an inhomogeneous magnetic field. We show that this approach can effectively overcome the field inhomogeneities, and greatly reduce the off-resonance effects during excitation. It is hoped that this new BASE technique can find wide applications in imaging and spectroscopy in vivo in the presence of large field inhomogeneities.